The Register's web site has been served by Apache running on Linux for some time. When the hardware was changed in December 2002, we eagerly took the opportunity to switch to Debian GNU/Linux. We were particularly attracted by Debian's reliability, stability, and flexibility, but most of all by its unmatched support for remote administration: since the system administrators and the systems themselves are separated by several hundred kilometers, it's especially important that as many tasks as possible can be accomplished remotely. Apt makes remote package management and upgrading trivial, and the Debian organization's enlightened and rapid response to security vulnerabilities lets us sleep easy in our beds.
As of this writing in April 2004, The Reg has all five of its public-facing servers running Debian, and no intention of moving to anything else. The Debian machines now provide services including DNS, email (including a mailing list for Reg readers), and the custom-built Perl content management system and its database, not to mention the public web site which regularly handles more than a million page impressions a day.